Melatonin Use Linked to Increased Heart Failure Risk
A recent study highlights a significant risk associated with prolonged melatonin use in adults suffering from insomnia. The research indicates that long-term melatonin users have nearly double the risk of developing heart failure compared to those who do not use the supplement.
Study Findings
Researchers analyzed health data from over 130,000 adults with insomnia and no prior heart failure diagnosis. The study compared individuals using melatonin for at least one year to those who never used it. Key findings include:
- Long-term melatonin users had a 90% greater chance of developing heart failure within five years.
- These users were nearly 3.5 times more likely to be hospitalized due to heart failure.
- The risk of death from any cause also increased for prolonged melatonin users.
Prescription Status and Regional Differences
In the United Kingdom, melatonin is only available with a prescription. Even among people who filled at least two prescriptions 90 days apart, the risk of heart failure was elevated by 82%.
"Adults with insomnia who took melatonin for at least a year had a much higher chance of developing heart failure."
"Long-term users were nearly 3.5 times more likely to be hospitalized for heart failure compared with nonusers."
Background on Melatonin Use
Melatonin is a widely used over-the-counter supplement in the United States, where nearly six million people take it to help fall asleep faster or extend sleep duration. This new evidence raises concerns about the safety of its long-term use.
Author’s Summary
Extended melatonin use in adults with insomnia notably increases the risk of heart failure, hospitalization, and mortality, indicating the need for cautious use and further research.