Common Supplement Shows Concerning Link to Heart Failure

Common Supplement Shows Concerning Link to Heart Failure

New research into a widely used sleeping aid has raised concerns about its long-term effects. An analysis involving over 130,000 adults with insomnia across several countries found that those prescribed melatonin for more than a year faced significantly higher health risks.

Study Findings

Context and Caution

The study's results are preliminary and have not yet undergone peer review, so they do not currently change existing health recommendations. Importantly, these findings do not prove that melatonin causes these risks but highlight the need for further long-term safety research.

About Melatonin

Melatonin is the fourth most popular natural supplement among adults in the US. It is generally considered safe and effective for short-term use, typically 1 to 2 months, especially for those who are not pregnant or breastfeeding. However, data on the safety of extended usage is limited.

Expert Insight

The researchers emphasized the importance of studying melatonin's long-term use more thoroughly as its popularity continues to increase.

The new findings were presented at the American Heart Association's Scientific Sessions.

Summary: Preliminary research suggests long-term melatonin use may increase heart failure risk, underscoring the need for further study on its safety beyond short-term use.

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ScienceAlert ScienceAlert — 2025-11-07