NFL Picks and Predictions for Week 6
With the NFL back in action, here are 3 plus-money bets to consider for Week 6.
By Spenser Davis, Published: Oct 12, 2025 · 8:30 AM EDT
Introduction to Week 6 NFL Picks
It's time for Week 6 of the NFL season, and we're exploring some plus-money NFL picks. Last week's NFL bold predictions went 2-1, resulting in a +1.17 unit overall gain. Since Week 3, picks in this story are up 2.16 units.
Week 6 Bold Predictions
Here are 3 bold predictions for this week in the NFL:
- Fading the Colts offense, despite their impressive performance, averaging 3.39 points per drive, which would be the highest this century if maintained throughout the season.
Since the start of Week 3, picks in this story are up 2.16 units.
Author's summary: NFL Week 6 plus-money bets analysis.
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