Familial Clustering Identified in Primary Hyperparathyroidism
Familial clustering was identified in primary hyperparathyroidism, as first-degree relatives were at higher risk than control patients.
First-degree relatives of patients with primary hyperparathyroidism are at greater risk of having the condition themselves, but a link to cancer risk among parents, siblings, and children is less certain, according to study findings published in the Journal of the Endocrine Society.
Prior research findings have suggested that primary hyperparathyroidism is associated with an elevated risk for malignancy, with a recent meta-analysis showing a pooled prevalence of 20% for any type of cancer among this population.
It is not known, however, whether first-degree relatives of patients with primary hyperparathyroidism carry an increased risk for either cancer or the thyroid condition.
Author's summary: Familial clustering found in primary hyperparathyroidism.
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